MedKoo Cat#: 124615 | Name: B-Raf IN 15
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

B-Raf IN 15 (Compound 7) is a BRAF inhibitor.

Chemical Structure

B-Raf IN 15
B-Raf IN 15
CAS#832107-31-0

Theoretical Analysis

MedKoo Cat#: 124615

Name: B-Raf IN 15

CAS#: 832107-31-0

Chemical Formula: C19H15N3OS

Exact Mass: 333.0936

Molecular Weight: 333.41

Elemental Analysis: C, 68.45; H, 4.53; N, 12.60; O, 4.80; S, 9.62

Price and Availability

Size Price Availability Quantity
100mg USD 1,250.00 2 Weeks
200mg USD 2,050.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 6,950.00 2 Weeks
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Related CAS #
No Data
Synonym
B-Raf IN 15; B-Raf IN-15; B Raf IN 15; Compound 7
IUPAC/Chemical Name
7-((pyridin-3-ylamino)(thiophen-3-yl)methyl)quinolin-8-ol
InChi Key
KSWFNFIKRRTNCX-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H15N3OS/c23-19-16(6-5-13-3-1-9-21-18(13)19)17(14-7-10-24-12-14)22-15-4-2-8-20-11-15/h1-12,17,22-23H
SMILES Code
OC1=C(C(C2=CSC=C2)NC3=CC=CN=C3)C=CC4=CC=CN=C14
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 333.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Qin J, Xie P, Ventocilla C, Zhou G, Vultur A, Chen Q, Liu Q, Herlyn M, Winkler J, Marmorstein R. Identification of a novel family of BRAF(V600E) inhibitors. J Med Chem. 2012 Jun 14;55(11):5220-30. doi: 10.1021/jm3004416. Epub 2012 May 18. PMID: 22537109; PMCID: PMC3383862.