(±)-LY 395756 | CAS# 852679-66-4 | mGlu2 agonist / mGlu3 antagonist

MedKoo Cat#: 574370 | Name: (±)-LY 395756

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(±)-LY 395756 is a selective metabotropic glutamate ligand for mGlu2 and mGlu3 receptors that acts as an agonist at mGlu2 and antagonist at mGlu3. (±)-LY 395756 is an analog of LY 354740.

Chemical Structure

(±)-LY 395756

CAS#852679-66-4

Theoretical Analysis

MedKoo Cat#: 574370

Name: (±)-LY 395756

CAS#: 852679-66-4

Chemical Formula: C9H13NO4

Exact Mass: 199.0845

Molecular Weight: 199.21

Elemental Analysis: C, 54.26; H, 6.58; N, 7.03; O, 32.13

Price and Availability

Size	Price	Availability	Quantity

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

No Data

Synonym

(±)-LY 395756

IUPAC/Chemical Name

(1S,2S,4R,5R,6S)-rel-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid

InChi Key

BQVZICWQBFTOJX-QNDZYWSYSA-N

InChi Code

InChI=1S/C9H13NO4/c1-3-2-9(10,8(13)14)6-4(3)5(6)7(11)12/h3-6H,2,10H2,1H3,(H,11,12)(H,13,14)/t3-,4+,5+,6+,9+/m1/s1

SMILES Code

O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])[C@H](C)C1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 199.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Dominguez et al (2005) Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate receptors: identification of a subtype selective mGlu2 receptor agonist. J.Med.Chem. 48 3605 PMID: 15887967