MedKoo Cat#: 124607 | Name: AH-357
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AH-357 (AH-357/02177012 or Anticancer agent 129 ), a quinoline derivative, is a potential anti-cancer agent.

Chemical Structure

AH-357
AH-357
CAS#135882-37-0

Theoretical Analysis

MedKoo Cat#: 124607

Name: AH-357

CAS#: 135882-37-0

Chemical Formula: C18H17N3

Exact Mass: 275.1422

Molecular Weight: 275.36

Elemental Analysis: C, 78.52; H, 6.22; N, 15.26

Price and Availability

Size Price Availability Quantity
100mg USD 1,350.00 2 Weeks
200mg USD 2,050.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 6,950.00 2 Weeks
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Related CAS #
No Data
Synonym
Anticancer agent 129; Anticancer agent-129; Anticancer agent129; AH-357/02177012;
IUPAC/Chemical Name
1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-amine
InChi Key
ZCZQCKJQIGWLFR-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H17N3/c19-17-14-8-4-5-9-16(14)20-18-15(17)10-11-21(18)12-13-6-2-1-3-7-13/h1-9H,10-12H2,(H2,19,20)
SMILES Code
NC1=C2C(N(CC3=CC=CC=C3)CC2)=NC4=CC=CC=C14
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 275.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Vaidya A, Jain AK, Kumar P, Kashaw SK, Agrawal RK. Predicting anti-cancer activity of quinoline derivatives: CoMFA and CoMSIA approach. J Enzyme Inhib Med Chem. 2011 Dec;26(6):854-61. doi: 10.3109/14756366.2011.567195. Epub 2011 Apr 8. PMID: 21476832.