MedKoo Cat#: 464862 | Name: DTA0100

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DTA0100 is a dual tubulin−topo II inhibitor.

Chemical Structure

DTA0100
DTA0100
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 464862

Name: DTA0100

CAS#: unknown

Chemical Formula: C13H22O5

Exact Mass: 258.1467

Molecular Weight: 258.31

Elemental Analysis: C, 60.45; H, 8.58; O, 30.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DTA0100; DTA 0100; DTA-0100;
IUPAC/Chemical Name
(E)-1-(methylperoxy)-4-((3-(methylperoxy)prop-1-en-1-yl)oxy)oct-2-yne
InChi Key
BDEKRRCMNKASLL-JXMROGBWSA-N
InChi Code
InChI=1S/C13H22O5/c1-4-5-8-13(9-6-11-17-14-2)16-10-7-12-18-15-3/h7,10,13H,4-5,8,11-12H2,1-3H3/b10-7+
SMILES Code
CCCCC(C#CCOOC)O/C=C/COOC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 258.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Podolski-Renić A, Banković J, Dinić J, Ríos-Luci C, Fernandes MX, Ortega N, Kovačević-Grujičić N, Martín VS, Padrón JM, Pešić M. DTA0100, dual topoisomerase II and microtubule inhibitor, evades paclitaxel resistance in P-glycoprotein overexpressing cancer cells. Eur J Pharm Sci. 2017 Jul 15;105:159-168. doi: 10.1016/j.ejps.2017.05.011. Epub 2017 May 11. PMID: 28502672. 2: Bordon E, Leon LG, Rios-Luci C, Lara PC, Padron JM. In vitro synergistic interaction between DTA0100 and radiation in human cancer cell lines. Anticancer Agents Med Chem. 2012 Oct 1;12(8):988-93. doi: 10.2174/187152012802650057. PMID: 22339062.