MedKoo Cat#: 124593 | Name: DC-Y13-27
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DC-Y13-27, a derivative of DC-Y13, is a YTHDF2 inhibitor (KD: 37.9 μM).

Chemical Structure

DC-Y13-27
DC-Y13-27
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124593

Name: DC-Y13-27

CAS#: N/A

Chemical Formula: C14H10N2O2S

Exact Mass: 270.0463

Molecular Weight: 270.31

Elemental Analysis: C, 62.21; H, 3.73; N, 10.36; O, 11.84; S, 11.86

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,650.00 2 Weeks
2g USD 5,650.00 2 Weeks
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Related CAS #
No Data
Synonym
DC-Y13-27; DC-Y13 27 ; DC Y13-27
IUPAC/Chemical Name
(E)-2-cyano-3-(5-(3-hydroxyphenyl)thiophen-2-yl)acrylamide
InChi Key
FCXTXGWIQGHISV-JXMROGBWSA-N
InChi Code
InChI=1S/C14H10N2O2S/c15-8-10(14(16)18)7-12-4-5-13(19-12)9-2-1-3-11(17)6-9/h1-7,17H,(H2,16,18)/b10-7+
SMILES Code
N#C/C(C(N)=O)=C\C1=CC=C(C2=CC(O)=CC=C2)S1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 270.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Wang L, Dou X, Chen S, Yu X, Huang X, Zhang L, Chen Y, Wang J, Yang K, Bugno J, Pitroda S, Ding X, Piffko A, Si W, Chen C, Jiang H, Zhou B, Chmura SJ, Luo C, Liang HL, He C, Weichselbaum RR. YTHDF2 inhibition potentiates radiotherapy antitumor efficacy. Cancer Cell. 2023 Jul 10;41(7):1294-1308.e8. doi: 10.1016/j.ccell.2023.04.019. Epub 2023 May 25. PMID: 37236197; PMCID: PMC10524856.