MC2791 | 1,4-DHP-based | SIRT3 activator

MedKoo Cat#: 124274 | Name: MC2791

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MC2791 is a 1,4-DHP-based SIRT3 activator

Chemical Structure

MC2791

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 124274

Name: MC2791

CAS#: N/A

Chemical Formula: C25H24O5

Exact Mass: 404.1600

Molecular Weight: 404.46

Elemental Analysis: C, 74.24; H, 5.98; O, 19.78

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MC2791; MC-2791; MC 2791

IUPAC/Chemical Name

diethyl 4-benzoyl-1,4-dihydro-[1,1'-biphenyl]-2,6-dicarboxylate

InChi Key

FVEGJOZENOKHSH-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H24O5/c1-3-29-24(27)20-15-19(23(26)18-13-9-6-10-14-18)16-21(25(28)30-4-2)22(20)17-11-7-5-8-12-17/h5-16,19,22H,3-4H2,1-2H3

SMILES Code

O=C(OCC)C1=CC(C(C2=CC=CC=C2)=O)C=C(C(OCC)=O)C1C3=CC=CC=C3

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 404.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Aventaggiato M, Barreca F, Vitiello L, Vespa S, Valente S, Rotili D, Mai A, Lotti LV, Sansone L, Russo MA, Bizzarri M, Ferretti E, Tafani M. Role of SIRT3 in Microgravity Response: A New Player in Muscle Tissue Recovery. Cells. 2023 Feb 22;12(5):691. doi: 10.3390/cells12050691. PMID: 36899828; PMCID: PMC10000945. 2: Nobile V, Palumbo F, Lanni S, Ghisio V, Vitali A, Castagnola M, Marzano V, Maulucci G, De Angelis C, De Spirito M, Pacini L, D'Andrea L, Ragno R, Stazi G, Valente S, Mai A, Chiurazzi P, Genuardi M, Neri G, Tabolacci E. Altered mitochondrial function in cells carrying a premutation or unmethylated full mutation of the FMR1 gene. Hum Genet. 2020 Feb;139(2):227-245. doi: 10.1007/s00439-019-02104-7. Epub 2020 Jan 9. PMID: 31919630.