MedKoo Cat#: 124127 | Name: Nor NOHA monoacetate
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nor NOHA monoacetate is a reversible, competitive arginase inhibitor (IC50 = 2 μM).

Chemical Structure

Nor NOHA monoacetate
Nor NOHA monoacetate
CAS#2250019-93-1 (mono acetate)

Theoretical Analysis

MedKoo Cat#: 124127

Name: Nor NOHA monoacetate

CAS#: 2250019-93-1 (mono acetate)

Chemical Formula: C7H16N4O5

Exact Mass: 0.0000

Molecular Weight: 236.23

Elemental Analysis: C, 35.59; H, 6.83; N, 23.72; O, 33.86

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,450.00 2 Weeks
500mg USD 2,950.00 2 Weeks
1g USD 4,650.00 2 Weeks
2g USD 6,450.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Synonym
Nor-NOHA (Monoacetate); Nor-NOHA Monoacetate; AKOS032962868;
IUPAC/Chemical Name
(S)-2-amino-4-(3-hydroxyguanidino)butanoic acid--acetic acid (1/1)
InChi Key
RYUGHGOGNIYFKU-DFWYDOINSA-N
InChi Code
InChI=1S/C5H12N4O3.C2H4O2/c6-3(4(10)11)1-2-8-5(7)9-12;1-2(3)4/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9);1H3,(H,3,4)/t3-;/m0./s1
SMILES Code
CC(O)=O.O=C(O)[C@@H](N)CCNC(NO)=N
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 236.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1, Ng KP, Manjeri A, Lee LM, Chan ZE, Tan CY, Tan QD, Majeed A, Lee KL, Chuah C, Suda T, Ong ST. The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target. PLoS One. 2018 Oct 11;13(10):e0205254. doi: 10.1371/journal.pone.0205254. PMID: 30307989; PMCID: PMC6181325. 2. Jung C, Gonon AT, Sjöquist PO, Lundberg JO, Pernow J. Arginase inhibition mediates cardioprotection during ischaemia-reperfusion. Cardiovasc Res. 2010 Jan 1;85(1):147-54. doi: 10.1093/cvr/cvp303. PMID: 19726439.