AhR agonist III11 is a novel, potent AhR agonist. It enhances the expression of AhR downstream target genes, triggering AhR nuclear translocation, and promoting differentiation of regulatory T cells. It exhibits good bioavailability (F = 87.40%) and strong therapeutic effects in a mouse model of ulcerative colitis at a dosage of 10 mg/kg
MedKoo Cat#: 130584
Name: AhR agonist III11
CAS#: AhR agonist III11
Chemical Formula: C17H17NO2
Exact Mass: 267.1259
Molecular Weight: 267.33
Elemental Analysis: C, 76.38; H, 6.41; N, 5.24; O, 11.97
The following data is based on the product molecular weight 267.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
