MedKoo Cat#: 130573 | Name: NSD2-PWWP1 inhibitor 38

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSD2-PWWP1 inhibitor 38 is a novel, potent, and selective NSD2-PWWP1 inhibitor. It binds to NSD2-PWWP1 and affects the expression of NSD2-regulated genes.

Chemical Structure

NSD2-PWWP1 inhibitor 38
NSD2-PWWP1 inhibitor 38
CAS#2797183-37-8

Theoretical Analysis

MedKoo Cat#: 130573

Name: NSD2-PWWP1 inhibitor 38

CAS#: 2797183-37-8

Chemical Formula: C29H31N5

Exact Mass: 449.2579

Molecular Weight: 449.60

Elemental Analysis: C, 77.47; H, 6.95; N, 15.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
NSD2-PWWP1-inhibitor-38, NSD2 PWWP1 inhibitor 38, NSD2 PWWP1 In 38, NSD2 PWWP1-In 38, NSD2 PWWP1-In-38, NSD2-PWWP1-In-38
IUPAC/Chemical Name
4-(4-(4-((4-Aminopiperidin-1-yl)methyl)-2,6-dimethylphenyl)-1-methyl-1H-imidazol-5-yl)-1-naphthonitrile
InChi Key
YELBNEVEPNGEGQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C29H31N5/c1-19-14-21(17-34-12-10-23(31)11-13-34)15-20(2)27(19)28-29(33(3)18-32-28)26-9-8-22(16-30)24-6-4-5-7-25(24)26/h4-9,14-15,18,23H,10-13,17,31H2,1-3H3
SMILES Code
N#CC1=C2C=CC=CC2=C(C3=C(C4=C(C)C=C(CN5CCC(N)CC5)C=C4C)N=CN3C)C=C1
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 449.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Li N, Yang H, Liu K, Zhou L, Huang Y, Cao D, Li Y, Sun Y, Yu A, Du Z, Yu F, Zhang Y, Wang B, Geng M, Li J, Xiong B, Xu S, Huang X, Liu T. Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors. J Med Chem. 2022 Jul 14;65(13):9459-9477. doi: 10.1021/acs.jmedchem.2c00709. Epub 2022 Jun 15. PMID: 35704853.