MedKoo Cat#: 130551 | Name: 6-NBDF

Description:

WARNING: This product is for research use only, not for human or veterinary use.

6-NBDF is a novel GLUT5 transporter-specific fluorescent probe. It is rapidly taken up into cell lines via GLUT5-expressing cancerous cells.

Chemical Structure

6-NBDF
6-NBDF
CAS#6-NBDF

Theoretical Analysis

MedKoo Cat#: 130551

Name: 6-NBDF

CAS#: 6-NBDF

Chemical Formula: C13H16N4O7

Exact Mass: 340.1019

Molecular Weight: 340.29

Elemental Analysis: C, 45.89; H, 4.74; N, 16.46; O, 32.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
6 NBDF, 6NBDF
IUPAC/Chemical Name
(3S,4S,5R)-2-(Hydroxymethyl)-2-methyl-5-(((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)methyl)tetrahydrofuran-3,4-diol
InChi Key
KPPNPVFWCLEWQL-ZLHSAUGSSA-N
InChi Code
InChI=1S/C13H16N4O7/c1-13(5-18)12(20)11(19)8(23-13)4-14-6-2-3-7(17(21)22)10-9(6)15-24-16-10/h2-3,8,11-12,14,18-20H,4-5H2,1H3/t8-,11-,12+,13?/m1/s1
SMILES Code
O[C@@H]1C(C)(CO)O[C@H](CNC2=CC=C([N+]([O-])=O)C3=NON=C32)[C@H]1O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 340.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Rana N, Aziz MA, Serya RAT, Lasheen DS, Samir N, Wuest F, Abouzid KAM, West FG. A Fluorescence-Based Assay to Probe Inhibitory Effect of Fructose Mimics on GLUT5 Transport in Breast Cancer Cells. ACS Bio Med Chem Au. 2022 Nov 7;3(1):51-61. doi: 10.1021/acsbiomedchemau.2c00056. PMID: 37101605; PMCID: PMC10125380. 2. Soueidan OM, Scully TW, Kaur J, Panigrahi R, Belovodskiy A, Do V, Matier CD, Lemieux MJ, Wuest F, Cheeseman C, West FG. Fluorescent Hexose Conjugates Establish Stringent Stereochemical Requirement by GLUT5 for Recognition and Transport of Monosaccharides. ACS Chem Biol. 2017 Apr 21;12(4):1087-1094. doi: 10.1021/acschembio.6b01101. Epub 2017 Mar 2. PMID: 28205432.