Mpro inhibitor 818 | CAS# 1142214-24-1 | Mpro Inhibitor

MedKoo Cat#: 130498 | Name: Mpro inhibitor 818

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mpro inhibitor 818 is a novel SARS-CoV-2 main protease fragment-like inhibitor. It has antiviral activity in vitro.

Chemical Structure

Mpro inhibitor 818

CAS#1142214-24-1

Theoretical Analysis

MedKoo Cat#: 130498

Name: Mpro inhibitor 818

CAS#: 1142214-24-1

Chemical Formula: C14H15ClN2O

Exact Mass: 262.0873

Molecular Weight: 262.74

Elemental Analysis: C, 64.00; H, 5.75; Cl, 13.49; N, 10.66; O, 6.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Mpro inhibitor-818, Mpro 818, Mpro-818

IUPAC/Chemical Name

2-Chloro-1-(8-methyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)ethan-1-one

InChi Key

AYMOQCHEQIBRIR-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H15ClN2O/c1-9-2-3-12-10(6-9)11-8-17(14(18)7-15)5-4-13(11)16-12/h2-3,6,16H,4-5,7-8H2,1H3

SMILES Code

O=C(N(C1)CCC(N2)=C1C3=C2C=CC(C)=C3)CCl

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 262.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Saramago LC, Santana MV, Gomes BF, Dantas RF, Senger MR, Oliveira Borges PH, Ferreira VNDS, Dos Santos Rosa A, Tucci AR, Dias Miranda M, Lukacik P, Strain-Damerell C, Owen CD, Walsh MA, Ferreira SB, Silva-Junior FP. AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro. J Chem Inf Model. 2023 May 8;63(9):2866-2880. doi: 10.1021/acs.jcim.3c00409. Epub 2023 Apr 14. PMID: 37058135; PMCID: PMC10124747.