MedKoo Cat#: 130497 | Name: Mpro inhibitor 737

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mpro inhibitor 737 is a novel SARS-CoV-2 main protease fragment-like inhibitor. It has antiviral activity in vitro models.

Chemical Structure

Mpro inhibitor 737
Mpro inhibitor 737
CAS#503855-51-4

Theoretical Analysis

MedKoo Cat#: 130497

Name: Mpro inhibitor 737

CAS#: 503855-51-4

Chemical Formula: C14H10N2O2

Exact Mass: 238.0742

Molecular Weight: 238.25

Elemental Analysis: C, 70.58; H, 4.23; N, 11.76; O, 13.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Mpro inhibitor-737, Mpro In 737, Mpro-In- 737, Mpro In-737
IUPAC/Chemical Name
1-(Pyridin-4-ylmethyl)indoline-2,3-dione
InChi Key
HHZNAUQZNZEDNI-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H10N2O2/c17-13-11-3-1-2-4-12(11)16(14(13)18)9-10-5-7-15-8-6-10/h1-8H,9H2
SMILES Code
O=C1N(CC2=CC=NC=C2)C3=C(C=CC=C3)C1=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 238.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Saramago LC, Santana MV, Gomes BF, Dantas RF, Senger MR, Oliveira Borges PH, Ferreira VNDS, Dos Santos Rosa A, Tucci AR, Dias Miranda M, Lukacik P, Strain-Damerell C, Owen CD, Walsh MA, Ferreira SB, Silva-Junior FP. AI-Driven Discovery of SARS-CoV-2 Main Protease Fragment-like Inhibitors with Antiviral Activity In Vitro. J Chem Inf Model. 2023 May 8;63(9):2866-2880. doi: 10.1021/acs.jcim.3c00409. Epub 2023 Apr 14. PMID: 37058135; PMCID: PMC10124747.