Anizatrectinib, also known as hTrkA-IN-1, is a potent and orally active inhibitor of TrkA kinase with an IC50 of 1.3 nM.
MedKoo Cat#: 130487
Name: Anizatrectinib free base
CAS#: 1824664-89-2 (free base)
Chemical Formula: C29H32FN7O2
Exact Mass: 529.2602
Molecular Weight: 529.62
Elemental Analysis: C, 65.77; H, 6.09; F, 3.59; N, 18.51; O, 6.04
The following data is based on the product molecular weight 529.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
