DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.
MedKoo Cat#: 206145
Name: DTP348
CAS#: 1383370-92-0
Chemical Formula: C6H11N5O4S
Exact Mass: 249.0532
Molecular Weight: 249.25
Elemental Analysis: C, 28.91; H, 4.45; N, 28.10; O, 25.68; S, 12.86
The following data is based on the product molecular weight 249.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
