HPPE is a specific nonelectrophilic and physiological Bach1 inhibitor via heme-binding sites of Bach1 protein. HPPE derepresses Bach1-mediated repression. HPPE induces up-regulation of Hmox1 mRNA is mediated by Bach1 inhibition in vivo.
MedKoo Cat#: 556226
Name: HPPE
CAS#: 1325721-55-8
Chemical Formula: C21H20F3N5O3S
Exact Mass: 479.1239
Molecular Weight: 479.48
Elemental Analysis: C, 52.61; H, 4.20; F, 11.89; N, 14.61; O, 10.01; S, 6.69
The following data is based on the product molecular weight 479.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
