JH-LPH-50, an LpxH inhibitor, has the potential to play a key role in the development of antibiotics against Gram-negative pathogens. JH-LPH-50 achieves its antimicrobial activity by chelating the dimanganese cluster in the active site of LpxH.
MedKoo Cat#: 130462
Name: JH-LPH-50
CAS#: N/A
Chemical Formula: C24H29ClF3N5O5S
Exact Mass: 591.1530
Molecular Weight: 592.03
Elemental Analysis: C, 48.69; H, 4.94; Cl, 5.99; F, 9.63; N, 11.83; O, 13.51; S, 5.42
The following data is based on the product molecular weight 592.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
