YCT529, an RAR-α inhibitor, is used as a contraceptive, with a 99% effectiveness. YCT529 acts as a potent and selective antagonist of the Vitamin A receptor retinoic acid receptor alpha (RAR-α). In studies on mice it produced a 99% reduction in sperm production, and it has proceeded to early stage human clinical trials as a potential male contraceptive.
MedKoo Cat#: 130447
Name: YCT529
CAS#: 2863670-67-9 (sodium)
Chemical Formula: C29H24NNaO3
Exact Mass: 457.1654
Molecular Weight: 457.50
Elemental Analysis: C, 76.13; H, 5.29; N, 3.06; Na, 5.03; O, 10.49
The following data is based on the product molecular weight 457.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
