NP256 is an inhibitor of CaERG6 that has the potential for use as an antifungal. The antifungal activity of NP256 stems from the inhibition ergosterol biosynthesis, the downregulation of the gene expression level in hyphal formation, by blocking biofilm formation, and disrupting morphological transition in C. albicans.
MedKoo Cat#: 130446
Name: NP256
CAS#: N/A
Chemical Formula: C37H58O8
Exact Mass: 630.4132
Molecular Weight: 630.86
Elemental Analysis: C, 70.44; H, 9.27; O, 20.29
The following data is based on the product molecular weight 630.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
