MedKoo Cat#: 532294 | Name: MRS 2693 trisodium salt
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor). MRS 2693 trisodium salt displays no activity at other P2Y subtypes.

Chemical Structure

MRS 2693 trisodium salt
MRS 2693 trisodium salt
CAS#1448858-83-0

Theoretical Analysis

MedKoo Cat#: 532294

Name: MRS 2693 trisodium salt

CAS#: 1448858-83-0

Chemical Formula: C9H10IN2Na3O12P2

Exact Mass: 595.8447

Molecular Weight: 596.00

Elemental Analysis: C, 18.14; H, 1.69; I, 21.29; N, 4.70; Na, 11.57; O, 32.21; P, 10.39

Price and Availability

Size Price Availability Quantity
1mg USD 445.00 2 Weeks
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Related CAS #
MRS 2693 trisodium salt (1448858-83-0); MRS2693 (93906-48-0).
Synonym
MRS 2693 trisodium salt; MRS 2693; MRS2693; MRS-2693.
IUPAC/Chemical Name
5-Iodouridine-5'-O-diphosphate trisodium salt
InChi Key
QWGVSYFNEAILDQ-FCIXCQMASA-K
InChi Code
InChI=1S/C9H13IN2O12P2.3Na/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(23-8)2-22-26(20,21)24-25(17,18)19;;;/h1,4-6,8,13-14H,2H2,(H,20,21)(H,11,15,16)(H2,17,18,19);;;/q;3*+1/p-3/t4-,5-,6-,8-;;;/m1.../s1
SMILES Code
O[C@@H]([C@H]([C@H](N1C(NC(C(I)=C1)=O)=O)O2)O)[C@H]2COP([O-])(OP([O-])([O-])=O)=O.[Na+].[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 596.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lee H, Koh BH, Yamasaki E, George NE, Sanders KM, Koh SD. UTP activates small-conductance Ca2+-activated K+ channels in murine detrusor PDGFRα+ cells. Am J Physiol Renal Physiol. 2015 Sep 15;309(6):F569-74. doi: 10.1152/ajprenal.00156.2015. Epub 2015 Jul 22. PubMed PMID: 26202222; PubMed Central PMCID: PMC4572394. 2: Obba S, Hizir Z, Boyer L, Selimoglu-Buet D, Pfeifer A, Michel G, Hamouda MA, Gonçalvès D, Cerezo M, Marchetti S, Rocchi S, Droin N, Cluzeau T, Robert G, Luciano F, Robaye B, Foretz M, Viollet B, Legros L, Solary E, Auberger P, Jacquel A. The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML. Autophagy. 2015;11(7):1114-29. doi: 10.1080/15548627.2015.1034406. PubMed PMID: 26029847; PubMed Central PMCID: PMC4590592. 3: Mamedova LK, Wang R, Besada P, Liang BT, Jacobson KA. Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol Res. 2008 Sep-Oct;58(3-4):232-9. doi: 10.1016/j.phrs.2008.08.004. Epub 2008 Aug 30. PubMed PMID: 18805489; PubMed Central PMCID: PMC2586120.