MedKoo Cat#: 130377 | Name: (S,R,S)-VL285 Phenol-PEG2-NH2 hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S,R,S)-VL285 Phenol-PEG2-NH2 hydrochloride is a building block of protein degraders and PROTAC research. (S,R,S)-VL285 Phenol-PEG2-NH2 hydrochloride is composed of a von Hippel-Lindau (VHL)-recruiting ligand, a PEG linker, and a pendant amine that reacts with a carboxylic acid on the target ligand.

Chemical Structure

(S,R,S)-VL285 Phenol-PEG2-NH2 hydrochloride
(S,R,S)-VL285 Phenol-PEG2-NH2 hydrochloride
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130377

Name: (S,R,S)-VL285 Phenol-PEG2-NH2 hydrochloride

CAS#: N/A

Chemical Formula: C35H46ClN5O7S

Exact Mass: 715.2806

Molecular Weight: 716.29

Elemental Analysis: C, 58.69; H, 6.47; Cl, 4.95; N, 9.78; O, 15.64; S, 4.48

Price and Availability

Size Price Availability Quantity
50mg USD 730.00 2 Weeks
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Related CAS #
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Synonym
(S,R,S)-VL285 Phenol-PEG2-NH2 hydrochloride; (S,R,S)-VL285 Phenol-PEG2-NH2 HCl
IUPAC/Chemical Name
(2R,4S)-N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxy-1-((R)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide hydrochloride
InChi Key
RJXJVEJULBIZRR-YSQLAWOQSA-N
InChi Code
InChI=1S/C35H45N5O7S.ClH/c1-22(2)31(40-19-26-6-4-5-7-28(26)34(40)43)35(44)39-20-27(41)17-29(39)33(42)37-18-25-9-8-24(32-23(3)38-21-48-32)16-30(25)47-15-14-46-13-12-45-11-10-36;/h4-9,16,21-22,27,29,31,41H,10-15,17-20,36H2,1-3H3,(H,37,42);1H/t27-,29+,31+;/m0./s1
SMILES Code
O=C([C@@H]1N(C([C@H](N(CC2=C3C=CC=C2)C3=O)C(C)C)=O)C[C@@H](O)C1)NCC4=CC=C(C5=C(C)N=CS5)C=C4OCCOCCOCCN.[H]Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 716.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL