HUP30 is a vasodilating agent. HUP30 antagonized both extracellular Ca(2+) influx and Ca(2+) mobilization from intracellular stores in response to phenylephrine: this effect was not modified by the presence of ODQ. I(Ba(L)) was blocked by HUP30 in a concentration-dependent as well as ODQ-independent manner. HUP30 are vasorelaxing agents that stimulate soluble guanylyl cyclase, activate K(+) channels, and block extracellular Ca(2+) influx.
MedKoo Cat#: 556214
Name: HUP30
CAS#: 312747-21-0
Chemical Formula: C14H15N3O3S
Exact Mass: 305.0834
Molecular Weight: 305.35
Elemental Analysis: C, 55.07; H, 4.95; N, 13.76; O, 15.72; S, 10.50
The following data is based on the product molecular weight 305.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
