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MedKoo Cat#: 130294 | Name: LP-600

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LP-600 is a conjugate of MECAM and ampicillin for use against E. coli and other drug-resistant Gram-negative pathogens and Gram-positive pathogens.

Chemical Structure

LP-600
LP-600
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130294

Name: LP-600

CAS#: N/A

Chemical Formula: C67H68N10O21S

Exact Mass: 1380.4281

Molecular Weight: 1381.39

Elemental Analysis: C, 58.26; H, 4.96; N, 10.14; O, 24.32; S, 2.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
LP-600; LP600; LP 600
IUPAC/Chemical Name
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-((R)-2-(3-(4-(4-oxo-4-((2,4,6-tris((2,3-diacetoxybenzamido)methyl)phenyl)amino)butyl)-1H-1,2,3-triazol-1-yl)propanamido)-2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChi Key
ARSMLLZMLQQMOG-DITPPKNNSA-N
InChi Code
InChI=1S/C67H68N10O21S/c1-34(78)93-48-22-13-19-45(56(48)96-37(4)81)60(86)68-30-40-28-42(31-69-61(87)46-20-14-23-49(94-35(2)79)57(46)97-38(5)82)53(43(29-40)32-70-62(88)47-21-15-24-50(95-36(3)80)58(47)98-39(6)83)71-51(84)25-12-18-44-33-76(75-74-44)27-26-52(85)72-54(41-16-10-9-11-17-41)63(89)73-55-64(90)77-59(66(91)92)67(7,8)99-65(55)77/h9-11,13-17,19-24,28-29,33,54-55,59,65H,12,18,25-27,30-32H2,1-8H3,(H,68,86)(H,69,87)(H,70,88)(H,71,84)(H,72,85)(H,73,89)(H,91,92)/t54-,55-,59+,65-/m1/s1
SMILES Code
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(CCN3N=NC(CCCC(NC4=C(CNC(C5=CC=CC(OC(C)=O)=C5OC(C)=O)=O)C=C(CNC(C6=CC=CC(OC(C)=O)=C6OC(C)=O)=O)C=C4CNC(C7=CC=CC(OC(C)=O)=C7OC(C)=O)=O)=O)=C3)=O)C8=CC=CC=C8)=O)N1C2=O)O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,381.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1.. Lai YH, Franke R, Pinkert L, Overwin H, Brönstrup M. Molecular Signatures of the Eagle Effect Induced by the Artificial Siderophore Conjugate LP-600 in E. coli. ACS Infect Dis. 2023 Mar 10;9(3):567-581. doi: 10.1021/acsinfecdis.2c00567. Epub 2023 Feb 10. PMID: 36763039.