BDM2 | HIV-1 IN-LEDGF/p75 allosteric inhibitor

MedKoo Cat#: 122938 | Name: BDM2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Newly disclosed HIV-1 antiretroviral is the first integrase-LEDGF/p75 allosteric HIV-1 inhibitor to clear Ph.

Chemical Structure

BDM2

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 122938

Name: BDM2

CAS#: N/A

Chemical Formula: C25H30O4

Exact Mass: 394.2100

Molecular Weight: 394.51

Elemental Analysis: C, 76.11; H, 7.67; O, 16.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BDM2;BDM 2;BDM-2

IUPAC/Chemical Name

(S)-2-(tert-butoxy)-2-(2-(chroman-6-yl)-3-cyclopropyl-6-methylphenyl)acetic acid

InChi Key

UDFCYQOJPMKLMT-QHCPKHFHSA-N

InChi Code

InChI=1S/C25H30O4/c1-15-7-11-19(16-8-9-16)22(21(15)23(24(26)27)29-25(2,3)4)18-10-12-20-17(14-18)6-5-13-28-20/h7,10-12,14,16,23H,5-6,8-9,13H2,1-4H3,(H,26,27)/t23-/m0/s1

SMILES Code

CC(C([C@H](OC(C)(C)C)C(O)=O)=C1C2=CC=C(OCCC3)C3=C2)=CC=C1C4CC4

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 394.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Nishinaka N, Hongo S, Zhou CJ, Shioda S, Takahashi R, Yamauchi Y, Ohashi T, Ohki T, Nakada N, Takeda F, Takeda M. Identification of the novel developmentally regulated gene, Bdm2, which is highly expressed in fetal rat brain. Brain Res Dev Brain Res. 2000 Mar 15;120(1):57-64. doi: 10.1016/s0165-3806(99)00191-1. PMID: 10727730. 2: Liu Q, Wang Y, Liu J, Liu X, Dong Y, Huang X, Zhen Z, Lv J, He W. Degradability and Properties of PBAT-Based Biodegradable Mulch Films in Field and Their Effects on Cotton Planting. Polymers (Basel). 2022 Aug 2;14(15):3157. doi: 10.3390/polym14153157. PMID: 35956671; PMCID: PMC9371060. 3: Huang Y, Yam YS, Lee CKC, Organ B, Zhou JL, Surawski NC, Chan EFC, Hong G. Tackling nitric oxide emissions from dominant diesel vehicle models using on- road remote sensing technology. Environ Pollut. 2018 Dec;243(Pt B):1177-1185. doi: 10.1016/j.envpol.2018.09.088. Epub 2018 Sep 20. PMID: 30266007.