LY-1 is a dual inhibitor of both PLpro and Mpro for the treatment of SARS-CoV-2, specifically targeting the replication process of the virus. LY-1 contains a warhead, which serves to covalently bond with the catalytic cysteine residue of the enzymes. LY-1 is an antiviral that has demonstrated potential for future use as a COVID-19 treatment.
MedKoo Cat#: 130193
Name: LY-1
CAS#: N/A
Chemical Formula: C20H18N4O3S
Exact Mass: 394.1100
Molecular Weight: 394.45
Elemental Analysis: C, 60.90; H, 4.60; N, 14.20; O, 12.17; S, 8.13
The following data is based on the product molecular weight 394.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
