MedKoo Cat#: 130191 | Name: OFH5503

Description:

WARNING: This product is for research use only, not for human or veterinary use.

OFH5503, which consists of a muscarinergic M3 receptor ligand linked to a dye, is used for measuring binding affinities using flow cytometry, and has shown promise as a vital tool for furthering research on muscarinergic receptors.

Chemical Structure

OFH5503
OFH5503
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130191

Name: OFH5503

CAS#: N/A

Chemical Formula: C58H64ClF2N11O4

Exact Mass: 1051.4799

Molecular Weight: 1052.67

Elemental Analysis: C, 66.18; H, 6.13; Cl, 3.37; F, 3.61; N, 14.64; O, 6.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
OFH5503; OFH 5503; OFH-5503
IUPAC/Chemical Name
5-(1-(5-(4-(6-(4-((((3'-chloro-4',5-difluoro-[1,1'-biphenyl]-2-yl)carbamoyl)oxy)methyl)piperidin-1-yl)hexyl)-1H-1,2,3-triazol-1-yl)pentyl)-1H-1,2,3-triazol-4-yl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3,10-dihydroacridin-9-yl)benzoate
InChi Key
OYWFGKOWALKMBK-UHFFFAOYSA-N
InChi Code
InChI=1S/C58H64ClF2N11O4/c1-68(2)43-16-19-46-53(33-43)62-54-34-44(69(3)4)17-20-47(54)56(46)45-18-13-40(30-49(45)57(73)74)55-36-72(67-65-55)27-11-7-10-26-71-35-42(64-66-71)12-8-5-6-9-25-70-28-23-38(24-29-70)37-76-58(75)63-52-22-15-41(60)32-48(52)39-14-21-51(61)50(59)31-39/h13-22,30-36,38H,5-12,23-29,37H2,1-4H3,(H2,63,73,74,75)
SMILES Code
O=C([O-])C1=CC(C2=CN(CCCCCN3N=NC(CCCCCCN4CCC(COC(NC5=CC=C(F)C=C5C6=CC=C(F)C(Cl)=C6)=O)CC4)=C3)N=N2)=CC=C1C7=C(C=C/8)C(NC9=C7C=CC(N(C)C)=C9)=CC8=[N+](C)/C
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,052.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Köckenberger J, Fischer O, Konopa A, Bergwinkl S, Mühlich S, Gmeiner P, Kutta RJ, Hübner H, Keller M, Heinrich MR. Synthesis, Characterization, and Application of Muscarinergic M3 Receptor Ligands Linked to Fluorescent Dyes. J Med Chem. 2022 Dec 22;65(24):16494-16509. doi: 10.1021/acs.jmedchem.2c01376. Epub 2022 Dec 9. PMID: 36484801.