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MedKoo Cat#: 130177 | Name: DBXRM

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DBXRM is a full A(3)AR agonist.

Chemical Structure

DBXRM
DBXRM
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 130177

Name: DBXRM

CAS#: N/A

Chemical Formula: C19H29N5O6

Exact Mass: 423.2118

Molecular Weight: 423.47

Elemental Analysis: C, 53.89; H, 6.90; N, 16.54; O, 22.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DBXRM; Dbxrm
IUPAC/Chemical Name
(2S,3S,4R,5R)-5-(1,3-dibutyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide
InChi Key
FOUQIXNUUYCGAU-MOROJQBDSA-N
InChi Code
InChI=1S/C19H29N5O6/c1-4-6-8-22-15-11(17(28)23(19(22)29)9-7-5-2)24(10-21-15)18-13(26)12(25)14(30-18)16(27)20-3/h10,12-14,18,25-26H,4-9H2,1-3H3,(H,20,27)/t12-,13+,14-,18+/m0/s1
SMILES Code
CCCCN1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](C(NC)=O)O3)C=N2)C(N(CCCC)C1=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 423.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Gao ZG, Jacobson KA. Translocation of arrestin induced by human A(3) adenosine receptor ligands in an engineered cell line: comparison with G protein-dependent pathways. Pharmacol Res. 2008 Apr;57(4):303-11. doi: 10.1016/j.phrs.2008.02.008. Epub 2008 Mar 8. PMID: 18424164; PMCID: PMC2409065. 2. Park KS, Hoffmann C, Kim HO, Padgett WL, Daly JW, Brambilla R, Motta C, Abbracchio MP, Jacobson KA. Activation and Desensitization of Rat A3-Adenosine Receptors by Selective Adenosine Derivatives and Xanthine-7-Ribosides. Drug Dev Res. 1998 Jun 1;44(2-3):97-105. doi: 10.1002/(SICI)1098-2299(199806/07)44:2/3<97::AID-DDR7>3.0.CO;2-5. PMID: 23487508; PMCID: PMC3589805. 3. Shin Y, Daly JW, Jacobson KA. Activation of Phosphoinositide Breakdown and Elevation of Intracellular Calcium in a Rat RBL-2H3 Mast Cell Line by Adenosine Analogs: Involvement of A(3)-Adenosine Receptors? Drug Dev Res. 1996 Sep 1;39(1):36-46. doi: 10.1002/(sici)1098-2299(19960901)39:1<36::aid-ddr5>3.0.co;2-l. PMID: 23087534; PMCID: PMC3475513.