CRD-733 is a PDE9A inhibitor. CRD-733 Reverses Pressure Overload-Induced Heart Failure. CRD-733 improves key hallmarks of HF including LV hypertrophy, LV dysfunction, left atrial dilation, and pulmonary edema after pressure overload in the mouse transverse aortic constriction HF model.
MedKoo Cat#: 122411
Name: CRD-733
CAS#: 917089-10-2 (free acid)
Chemical Formula: C15H10Cl2N2O3S
Exact Mass: 367.9789
Molecular Weight: 369.22
Elemental Analysis: C, 48.80; H, 2.73; Cl, 19.20; N, 7.59; O, 13.00; S, 8.68
The following data is based on the product molecular weight 369.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
