BP Lipid 223 is an pentanolamine lipid with both ester bonds located adjacent to C6 relative to the amine head. The introduction of ester linkages can improve the clearance of the lipid in the liver. This compound is analgous to ALC-0315. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile.
MedKoo Cat#: 122311
Name: BP Lipid 223
CAS#: 2036272-56-5
Chemical Formula: C49H97NO5
Exact Mass: 779.7367
Molecular Weight: 780.32
Elemental Analysis: C, 75.42; H, 12.53; N, 1.80; O, 10.25
The following data is based on the product molecular weight 780.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
