BP Lipid 219 is an amine ionizable lipid analogous to BP-25498 (ALC-0315). The propanolamine lipid head enhances encapsulation of mRNA. The lipid has identical ester bonds located adjacent to C7 relative to the amine nitrogen. The lipid can be used for mRNA-based therapies which depends on the availability of a safe and efficient delivery vehicle.
MedKoo Cat#: 122307
Name: BP Lipid 219
CAS#: N/A
Chemical Formula: C49H97NO5
Exact Mass: 779.7367
Molecular Weight: 780.32
Elemental Analysis: C, 75.42; H, 12.53; N, 1.80; O, 10.25
The following data is based on the product molecular weight 780.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |