BP Lipid 153 is an amino ionizable lipid with ester bonds located at C8 and C7 position relative to nitrogen. The ester linkages are introduced to improve tissue clearance. The propanolamine head can effectively enhance mRNA encapsulation. The primary ester at C8 position contains 9 carbons lipid tail. The ionizable lipid can be used for mRNA delivery due to its excellent physiochemical properties.
MedKoo Cat#: 122301
Name: BP Lipid 153
CAS#: N/A
Chemical Formula: C44H87NO5
Exact Mass: 709.6584
Molecular Weight: 710.18
Elemental Analysis: C, 74.42; H, 12.35; N, 1.97; O, 11.26
The following data is based on the product molecular weight 710.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
