P131 is a PROTAC molecule comprised of Pomalidomide-based cereblon ligand and IBT6A, linked by a PEG 3 chain. P131 was initial developed by Sun (2018) that can degrade both wild-type and C481S mutant BTK with nanomolar potencies.
MedKoo Cat#: 122207
Name: P131
CAS#: N/A
Chemical Formula: C46H48N12O9
Exact Mass: 912.3667
Molecular Weight: 912.97
Elemental Analysis: C, 60.52; H, 5.30; N, 18.41; O, 15.77
The following data is based on the product molecular weight 912.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
