MedKoo Cat#: 122193 | Name: Thalidomide-O-PEG2-NHS ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

E3 ligase ligand-linker conjugate, Thalidomide-O-PEG2-NHS ester, is synthesized compound that incorporates the Thalidomide based cereblon ligand and the PEG linker used in PROTAC technology.

Chemical Structure

Thalidomide-O-PEG2-NHS ester
Thalidomide-O-PEG2-NHS ester
CAS#2639395-34-7

Theoretical Analysis

MedKoo Cat#: 122193

Name: Thalidomide-O-PEG2-NHS ester

CAS#: 2639395-34-7

Chemical Formula: C24H25N3O11

Exact Mass: 531.1489

Molecular Weight: 531.47

Elemental Analysis: C, 54.24; H, 4.74; N, 7.91; O, 33.11

Price and Availability

Size Price Availability Quantity
100mg USD 850.00 2 Weeks
250mg USD 1,450.00 2 Weeks
500mg USD 2,500.00 2 Weeks
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Related CAS #
No Data
Synonym
Thalidomide-O-PEG2-NHS ester
IUPAC/Chemical Name
2,5-dioxopyrrolidin-1-yl 3-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ethoxy)ethoxy)propanoate
InChi Key
PJBAJOQKKDCTDR-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H25N3O11/c28-17-5-4-15(22(32)25-17)26-23(33)14-2-1-3-16(21(14)24(26)34)37-13-12-36-11-10-35-9-8-20(31)38-27-18(29)6-7-19(27)30/h1-3,15H,4-13H2,(H,25,28,32)
SMILES Code
O=C1C2=CC=CC(OCCOCCOCCC(ON3C(CCC3=O)=O)=O)=C2C(N1C(CC4)C(NC4=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 531.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL