MedKoo Cat#: 122197 | Name: Thalidomide-O-PEG5-Tosyl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Thalidomide-O-PEG5-Tosyl is a molecule that incorporates the Thalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology. It is reactive with nucleophiles such as amine, hydroxy containing molecules.

Chemical Structure

Thalidomide-O-PEG5-Tosyl
Thalidomide-O-PEG5-Tosyl
CAS#2414905-34-1

Theoretical Analysis

MedKoo Cat#: 122197

Name: Thalidomide-O-PEG5-Tosyl

CAS#: 2414905-34-1

Chemical Formula: C30H36N2O12S

Exact Mass: 648.1989

Molecular Weight: 648.68

Elemental Analysis: C, 55.55; H, 5.59; N, 4.32; O, 29.60; S, 4.94

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
250mg USD 1,450.00 2 Weeks
500mg USD 2,450.00 2 Weeks
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Related CAS #
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Synonym
Thalidomide-O-PEG5-Tosyl
IUPAC/Chemical Name
4-((14-((di(l1-oxidanyl)(p-tolyl)-l4-sulfanyl)oxy)-3,6,9,12-tetraoxatetradecyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
InChi Key
JMGZBYJZCMGZII-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H36N2O12S/c1-21-5-7-22(8-6-21)45(37,38)44-20-18-42-16-14-40-12-11-39-13-15-41-17-19-43-25-4-2-3-23-27(25)30(36)32(29(23)35)24-9-10-26(33)31-28(24)34/h2-8,24H,9-20H2,1H3,(H,31,33,34)
SMILES Code
O=C1NC(C(N2C(C(C(OCCOCCOCCOCCOCCOS([O])([O])C3=CC=C(C)C=C3)=CC=C4)=C4C2=O)=O)CC1)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 648.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL