MedKoo Cat#: 122172 | Name: (S, R, S)-AHPC-PEG8-NHS ester
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S, R, S)-AHPC-PEG8-NHS ester is PROTAC linker that incorporates an E3 ligase ligand with a PEG4 spacer PEG4 arm increases the molecule's solubility. NHS ester group is very reactive with amine molecule.

Chemical Structure

(S, R, S)-AHPC-PEG8-NHS ester
(S, R, S)-AHPC-PEG8-NHS ester
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 122172

Name: (S, R, S)-AHPC-PEG8-NHS ester

CAS#: N/A

Chemical Formula: C46H69N5O16S

Exact Mass: 979.4460

Molecular Weight: 980.14

Elemental Analysis: C, 56.37; H, 7.10; N, 7.15; O, 26.12; S, 3.27

Price and Availability

Size Price Availability Quantity
50mg USD 800.00 2 Weeks
100mg USD 1,450.00 2 Weeks
250mg USD 2,350.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
(S, R, S)-AHPC-PEG8-NHS ester
IUPAC/Chemical Name
2,5-dioxopyrrolidin-1-yl 30-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-31,31-dimethyl-28-oxo-4,7,10,13,16,19,22,25-octaoxa-29-azadotriacontanoate
InChi Key
FROVIXFLHMSAQR-CGQOHYFOSA-N
InChi Code
InChI=1S/C46H69N5O16S/c1-33-42(68-32-48-33)35-7-5-34(6-8-35)30-47-44(57)37-29-36(52)31-50(37)45(58)43(46(2,3)4)49-38(53)11-13-59-15-17-61-19-21-63-23-25-65-27-28-66-26-24-64-22-20-62-18-16-60-14-12-41(56)67-51-39(54)9-10-40(51)55/h5-8,32,36-37,43,52H,9-31H2,1-4H3,(H,47,57)(H,49,53)/t36-,37+,43?/m1/s1
SMILES Code
CC(N=CS1)=C1C2=CC=C(C=C2)CNC([C@H](C[C@@H](O)C3)N3C(C(C(C)(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O)=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 980.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL