MedKoo Cat#: 122170 | Name: (S, R, S)-AHPC-PEG4-NHS ester
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S, R, S)-AHPC-PEG4-NHS ester is a PROTAC linker that incorporates an E3 ligase ligand with a PEG4 spacer to empower PROTAC medicine chemistry. It is is reactive with amine molecule. PEG4 arm increases the molecule's solubility.

Chemical Structure

(S, R, S)-AHPC-PEG4-NHS ester
(S, R, S)-AHPC-PEG4-NHS ester
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 122170

Name: (S, R, S)-AHPC-PEG4-NHS ester

CAS#: N/A

Chemical Formula: C38H53N5O12S

Exact Mass: 803.3411

Molecular Weight: 803.93

Elemental Analysis: C, 56.77; H, 6.65; N, 8.71; O, 23.88; S, 3.99

Price and Availability

Size Price Availability Quantity
100mg USD 850.00 2 Weeks
250mg USD 1,450.00 2 Weeks
500mg USD 2,450.00 2 Weeks
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Related CAS #
No Data
Synonym
(S, R, S)-AHPC-PEG4-NHS ester
IUPAC/Chemical Name
2,5-dioxopyrrolidin-1-yl 18-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-19,19-dimethyl-16-oxo-4,7,10,13-tetraoxa-17-azaicosanoate
InChi Key
NRGOXURBVINXIF-AUYWKQLASA-N
InChi Code
InChI=1S/C38H53N5O12S/c1-25-34(56-24-40-25)27-7-5-26(6-8-27)22-39-36(49)29-21-28(44)23-42(29)37(50)35(38(2,3)4)41-30(45)11-13-51-15-17-53-19-20-54-18-16-52-14-12-33(48)55-43-31(46)9-10-32(43)47/h5-8,24,28-29,35,44H,9-23H2,1-4H3,(H,39,49)(H,41,45)/t28-,29+,35?/m1/s1
SMILES Code
CC(N=CS1)=C1C2=CC=C(C=C2)CNC([C@H](C[C@@H](O)C3)N3C(C(C(C)(C)C)NC(CCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O)=O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 803.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL