MedKoo Cat#: 122164 | Name: (S, R, S)-AHPC-PEG2-acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S, R, S)-AHPC-PEG2-acid is a syntheticPROTAC linker molecule that incorporates an E3 ligase ligand with a PEG linker to empower PROTAC drug research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media.

Chemical Structure

(S, R, S)-AHPC-PEG2-acid
(S, R, S)-AHPC-PEG2-acid
CAS#2172820-09-4

Theoretical Analysis

MedKoo Cat#: 122164

Name: (S, R, S)-AHPC-PEG2-acid

CAS#: 2172820-09-4

Chemical Formula: C30H42N4O8S

Exact Mass: 618.2723

Molecular Weight: 618.75

Elemental Analysis: C, 58.24; H, 6.84; N, 9.06; O, 20.69; S, 5.18

Price and Availability

Size Price Availability Quantity
100mg USD 800.00 2 Weeks
250mg USD 1,450.00 2 Weeks
500mg USD 2,550.00 2 Weeks
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Related CAS #
No Data
Synonym
(S, R, S)-AHPC-PEG2-acid
IUPAC/Chemical Name
3-(2-(3-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)ethoxy)propanoic acid
InChi Key
SIVZLYPNCHCMRW-QSEAXJEQSA-N
InChi Code
InChI=1S/C30H42N4O8S/c1-19-26(43-18-32-19)21-7-5-20(6-8-21)16-31-28(39)23-15-22(35)17-34(23)29(40)27(30(2,3)4)33-24(36)9-11-41-13-14-42-12-10-25(37)38/h5-8,18,22-23,27,35H,9-17H2,1-4H3,(H,31,39)(H,33,36)(H,37,38)/t22-,23+,27-/m1/s1
SMILES Code
CC(C)(C)[C@@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)NC(CCOCCOCCC(O)=O)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 618.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL