N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester is a novel cysteine binder coupled to a terminal NHS ester bound by a PEG linker. The divinyltriazine works by stapling of two cysteine residues to form macrocyclic peptides from their unprotected linear counterparts. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
MedKoo Cat#: 122096
Name: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester
CAS#: N/A
Chemical Formula: C25H36N6O9
Exact Mass: 564.2544
Molecular Weight: 564.60
Elemental Analysis: C, 53.18; H, 6.43; N, 14.89; O, 25.50
The following data is based on the product molecular weight 564.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
