Quercinol | CAS#2650844-67-8 | Anti-inflammatory agent

MedKoo Cat#: 145078 | Name: Quercinol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quercinol is also known as (-)-(2S)-2-hydroxymethyl-2-methyl-6-hydroxychromene. Quercinol exhibits broad anti-inflammatory activity against enzymes such as cyclooxygenase 2 (COX-2), xanthine oxidase (XO), and horseradish peroxidase (HRP) at micromolar concentrations, suggesting its potential as a therapeutic agent for inflammatory conditions.

Chemical Structure

Quercinol

CAS#2650844-67-8

Theoretical Analysis

MedKoo Cat#: 145078

Name: Quercinol

CAS#: 2650844-67-8

Chemical Formula: C11H12O3

Exact Mass: 192.0786

Molecular Weight: 192.21

Elemental Analysis: C, 68.74; H, 6.29; O, 24.97

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Quercinol;

IUPAC/Chemical Name

2-methoxy-2-methyl-2H-chromen-6-ol

InChi Key

DLZKKUHAZDHCSL-UHFFFAOYSA-N

InChi Code

1S/C11H12O3/c1-11(13-2)6-5-8-7-9(12)3-4-10(8)14-11/h3-7,12H,1-2H3

SMILES Code

COC1(C)OC2=CC=C(O)C=C2C=C1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 192.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gebhardt P, Dornberger K, Gollmick FA, Gräfe U, Härtl A, Görls H, Schlegel B, Hertweck C. Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill). Bioorg Med Chem Lett. 2007 May 1;17(9):2558-60. doi: 10.1016/j.bmcl.2007.02.008. Epub 2007 Feb 7. PMID: 17346963. 2: Sekimoto M, Hattori Y, Morimura K, Hirota M, Makabe H. Asymmetric syntheses of daedalin A and quercinol and their tyrosinase inhibitory activity. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1063-4. doi: 10.1016/j.bmcl.2009.12.034. Epub 2009 Dec 11. PMID: 20036119.