Propargyl-PEG4-S-PEG4-t-butyl ester is a PEG linker containing a propargyl group and t-butyl group. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. t-butyl ester is a better leaving group compared to a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media.
MedKoo Cat#: 122029
Name: Propargyl-PEG4-S-PEG4-t-butyl ester
CAS#: 2055041-18-2
Chemical Formula: C26H48O10S
Exact Mass: 552.2968
Molecular Weight: 552.72
Elemental Analysis: C, 56.50; H, 8.75; O, 28.95; S, 5.80
The following data is based on the product molecular weight 552.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
