MedKoo Cat#: 121174 | Name: (S,R,S)-AHPC-benzyl-piperazine HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(S,R,S)-AHPC-benzyl-piperazine HCl is a ProTAC building block. (S,R,S)-AHPC-benzyl-piperazine HCl enables the synthesis of molecules for targeted protein degradation. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand, a rigid linker, and a pendant amine for reactivity with a carboxylic acid on the target ligand. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to Medkoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

(S,R,S)-AHPC-benzyl-piperazine HCl
(S,R,S)-AHPC-benzyl-piperazine HCl
CAS#Unknown

Theoretical Analysis

MedKoo Cat#: 121174

Name: (S,R,S)-AHPC-benzyl-piperazine HCl

CAS#: Unknown

Chemical Formula: C34H45ClN6O4S

Exact Mass: 668.2912

Molecular Weight: 669.28

Elemental Analysis: C, 61.02; H, 6.78; Cl, 5.30; N, 12.56; O, 9.56; S, 4.79

Price and Availability

Size Price Availability Quantity
50mg USD 1,250.00 Back order
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Related CAS #
No Data
Synonym
(S,R,S)-AHPC-benzyl-piperazine hydrochloride; (S,R,S)-AHPC-benzyl-piperazine HCl
IUPAC/Chemical Name
(2S,4R)-1-((S)-3,3-dimethyl-2-(4-(piperazin-1-ylmethyl)benzamido)butanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
InChi Key
BJUBAOUCAWDLBU-WIQFMUTLSA-N
InChi Code
InChI=1S/C34H44N6O4S.ClH/c1-22-29(45-21-37-22)25-9-5-23(6-10-25)18-36-32(43)28-17-27(41)20-40(28)33(44)30(34(2,3)4)38-31(42)26-11-7-24(8-12-26)19-39-15-13-35-14-16-39;/h5-12,21,27-28,30,35,41H,13-20H2,1-4H3,(H,36,43)(H,38,42);1H/t27-,28+,30-;/m1./s1
SMILES Code
O=C(NCC(C=C1)=CC=C1C2=C(C)N=CS2)[C@H]3N(C[C@@H](C3)O)C([C@@H](NC(C4=CC=C(CN5CCNCC5)C=C4)=O)C(C)(C)C)=O.Cl
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 669.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL