(S,R,S)-AHPC-benzyl-piperazine HCl is a ProTAC building block. (S,R,S)-AHPC-benzyl-piperazine HCl enables the synthesis of molecules for targeted protein degradation. This conjugate contains a von Hippel-Lindau (VHL)-recruiting ligand, a rigid linker, and a pendant amine for reactivity with a carboxylic acid on the target ligand. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to Medkoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 121174
Name: (S,R,S)-AHPC-benzyl-piperazine HCl
CAS#: Unknown
Chemical Formula: C34H45ClN6O4S
Exact Mass: 668.2912
Molecular Weight: 669.28
Elemental Analysis: C, 61.02; H, 6.78; Cl, 5.30; N, 12.56; O, 9.56; S, 4.79
The following data is based on the product molecular weight 669.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |