MedKoo Cat#: 461630 | Name: Cyphenothrin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cyphenothrin is a synthetic pyrethroid insecticide. It is effective against cockroaches that have developed resistance to organophosphorous and carbamate insecticides.

Chemical Structure

Cyphenothrin
Cyphenothrin
CAS#39515-40-7

Theoretical Analysis

MedKoo Cat#: 461630

Name: Cyphenothrin

CAS#: 39515-40-7

Chemical Formula: C24H25NO3

Exact Mass: 375.1834

Molecular Weight: 375.46

Elemental Analysis: C, 76.77; H, 6.71; N, 3.73; O, 12.78

Price and Availability

Size Price Availability Quantity
100mg USD 350.00 2 Weeks
1g USD 1,250.00 2 Weeks
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Related CAS #
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Synonym
Cyphenothrin; Gokilaht; S 2703; S-2703; S2703;
IUPAC/Chemical Name
cyano(3-phenoxyphenyl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
InChi Key
FJDPATXIBIBRIM-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H25NO3/c1-16(2)13-20-22(24(20,3)4)23(26)28-21(15-25)17-9-8-12-19(14-17)27-18-10-6-5-7-11-18/h5-14,20-22H,1-4H3
SMILES Code
O=C(C1C(C)(C)C1/C=C(C)\C)OC(C#N)C2=CC=CC(OC3=CC=CC=C3)=C2
Appearance
Purity
>98% (racemic mixture)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 375.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Driver JH, Ross JH, Holden LR, Selim S, Sharp JK, Carlson D, Nouvel L. Cyphenothrin Flea and Tick Squeeze-On for Dogs: Evaluation of Potential Health Risks Based on the Results of Observational Biological Monitoring. J Toxicol Environ Health A. 2015;78(17):1105-21. doi: 10.1080/15287394.2015.1050712. Epub 2015 Aug 20. PubMed PMID: 26291751. 2: Carithers D, Everett WR, Gross SJ, Solanki R. Efficacy of a proprietary formulation of fipronil/(S)-methoprene/cyphenothrin against Ixodes scapularis tick infestations on dogs. Parasit Vectors. 2015 Jul 17;8:379. doi: 10.1186/s13071-015-0992-1. PubMed PMID: 26182973; PubMed Central PMCID: PMC4504346. 3: Ren X, Chen L. Quantum dots coated with molecularly imprinted polymer as fluorescence probe for detection of cyphenothrin. Biosens Bioelectron. 2015 Feb 15;64:182-8. doi: 10.1016/j.bios.2014.08.086. Epub 2014 Sep 6. PubMed PMID: 25218102. 4: Case KM, Vega NM, Gupta RC, Lasher MA, Canerdy TD. Safety Evaluation of Parastar(®) Plus in Dogs and Assessment of Transferable Residue of Fipronil and Cyphenothrin from Dogs to Humans. Front Vet Sci. 2016 Sep 30;3:89. eCollection 2016. PubMed PMID: 27747219; PubMed Central PMCID: PMC5043066. 5: Erkmen B, Caliskan M, Yerli SV. Histopathological effects of cyphenothrin on the gills of Lebistes reticulatus. Vet Hum Toxicol. 2000 Feb;42(1):5-7. PubMed PMID: 10670076. 6: Tilak R, Agrawal VK, Dutta J. Field performance of cyphenothrin: an integrated insecticide strategy against German cockroaches (Dictyoptera: Blatellidae). J Vector Borne Dis. 2005 Jun;42(2):68-73. PubMed PMID: 16161703. 7: Fourie JJ, Fourie LJ, Horak IG, Snyman MG. The efficacy of a topically applied combination of cyphenothrin and pyriproxyfen against the southern African yellow dog tick, Haemaphysalis elliptica, and the cat flea, Ctenocephalides felis, on dogs. J S Afr Vet Assoc. 2010 Mar;81(1):33-6. PubMed PMID: 20649152. 8: Mittal PK, Sreehari U, Razdan RK, Dash AP. Efficacy of Cyphenothrin (Gokilaht-S 5% EC) as space spray against mosquitoes in sentinel cages. J Vector Borne Dis. 2009 Sep;46(3):241-3. PubMed PMID: 19724090. 9: Itoh T, Kurihara T. Efficacy of permethrin- and cyphenothrin-impregnated nettings against Culex pipiens pallens. J Am Mosq Control Assoc. 1992 Mar;8(1):84-5. PubMed PMID: 1583496. 10: Hao XL, Kuang H, Li YL, Yuan Y, Peng CF, Chen W, Wang LB, Xu CL. Development of an enzyme-linked immunosorbent assay for the alpha-cyano pyrethroids multiresidue in Tai lake water. J Agric Food Chem. 2009 Apr 22;57(8):3033-9. doi: 10.1021/jf803807b. PubMed PMID: 19368347. 11: Yap HH, Lee YW, Zairi J, Jahangir K, Adanan CR. Indoor thermal fogging application of pesguard FG 161, a mixture of d-tetramethrin and cyphenothrin, using portable sprayer against vector mosquitoes in the tropical environment. J Am Mosq Control Assoc. 2001 Mar;17(1):28-32. PubMed PMID: 11345415. 12: Romero A, Ares I, Ramos E, Castellano V, Martínez M, Martínez-Larrañaga MR, Anadón A, Martínez MA. Evidence for dose-additive effects of a type II pyrethroid mixture. In vitro assessment. Environ Res. 2015 Apr;138:58-66. doi: 10.1016/j.envres.2015.02.008. Epub 2015 Feb 16. PubMed PMID: 25688004. 13: Akıner MM, Cağlar SS. Monitoring of five different insecticide resistance status in Turkish house fly Musca domestica L. (Diptera: Muscidae) populations and the relationship between resistance and insecticide usage profile. Turkiye Parazitol Derg. 2012;36(2):87-91. doi: 10.5152/tpd.2012.21. PubMed PMID: 22801912. 14: Mongkalangoon P, Grieco JP, Achee NL, Suwonkerd W, Chareonviriyaphap T. Irritability and repellency of synthetic pyrethroids on an Aedes aegypti population from Thailand. J Vector Ecol. 2009 Dec;34(2):217-24. doi: 10.1111/j.1948-7134.2009.00029.x. PubMed PMID: 20836825. 15: Germant OM, Shashina NI. [EFFECT OF PYRETHROIDS ON TAIGA TICKS (IXODES PERSULCATUS IXODIDAE)]. Med Parazitol (Mosk). 2016 Jan-Mar;(1):60-2. Russian. PubMed PMID: 27029149. 16: Yan H, Qiao F, Tian M, Row KH. Simultaneous determination of nine pyrethroids in indoor insecticide products by capillary gas chromatography. J Pharm Biomed Anal. 2010 Feb 5;51(3):774-7. doi: 10.1016/j.jpba.2009.09.048. Epub 2009 Oct 7. PubMed PMID: 19875265. 17: Mikhail MW, Al-Bursheed KM, Allam KA. Susceptibility of Culex pipiens complex to some insecticides in Qatar. J Egypt Soc Parasitol. 2007 Dec;37(3):893-902. PubMed PMID: 18383791. 18: Raeppel C, Appenzeller BM, Millet M. Determination of seven pyrethroids biocides and their synergist in indoor air by thermal-desorption gas chromatography/mass spectrometry after sampling on Tenax TA ® passive tubes. Talanta. 2015 Jan;131:309-14. doi: 10.1016/j.talanta.2014.07.098. Epub 2014 Aug 8. PubMed PMID: 25281107. 19: Ma G, Chen L. Development of magnetic molecularly imprinted polymers based on carbon nanotubes - application for trace analysis of pyrethroids in fruit matrices. J Chromatogr A. 2014 Feb 14;1329:1-9. doi: 10.1016/j.chroma.2013.12.079. Epub 2014 Jan 2. PubMed PMID: 24418237. 20: Fernández-Alvarez M, Lores M, Llompart M, García-Jares C, Cela R. The photochemical behaviour of five household pyrethroid insecticides and a synergist as studied by photo-solid-phase microextraction. Anal Bioanal Chem. 2007 Jul;388(5-6):1235-47. Epub 2007 May 10. PubMed PMID: 17492275.