GDC-2394, also known as RO7440688, is a A Potent and Selective NLRP3 Inhibitor with an in vitro and in vivo safety profile suitable for advancement into human clinical trials. GDC 2394 Inhibits In Vivo Production of IL-1β in an Acute Mouse Peritonitis Model. GDC 2394 Reduces Paw Swelling and Pain in a Functional Rat Model of Gouty Arthritis.
MedKoo Cat#: 408181
Name: GDC-2394
CAS#: 2238822-07-4 (S-isomer)
Chemical Formula: C20H25N5O4S
Exact Mass: 431.1627
Molecular Weight: 431.51
Elemental Analysis: C, 55.67; H, 5.84; N, 16.23; O, 14.83; S, 7.43
The following data is based on the product molecular weight 431.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
