MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 121123 | Name: 8RK59

Description:

WARNING: This product is for research use only, not for human or veterinary use.

8RK59 is a PARK7 inhibitor.

Chemical Structure

8RK59
8RK59
CAS#2705841-53-6

Theoretical Analysis

MedKoo Cat#: 121123

Name: 8RK59

CAS#: 2705841-53-6

Chemical Formula: C33H39BF2N10O2S

Exact Mass: 688.3039

Molecular Weight: 688.61

Elemental Analysis: C, 57.56; H, 5.71; B, 1.57; F, 5.52; N, 20.34; O, 4.65; S, 4.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
8RK59; 8-RK59; 8 RK59; 8RK-59; 8-RK-59; 8 RK-59; 8RK 59; 8-RK 59; 8 RK 59
IUPAC/Chemical Name
(S)-1-cyano-N-(5-(2-(4-(4-(5,5-difluoro-1,3,7,9-tetramethyl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)butyl)-1H-1,2,3-triazol-1-yl)acetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)pyrrolidine-3-carboxamide
InChi Key
DHXYPFJKDQWPKY-DEOSSOPVSA-N
InChi Code
InChI=1S/C33H39BF2N10O2S/c1-20-13-22(3)45-30(20)26(31-21(2)14-23(4)46(31)34(45,35)36)8-6-5-7-25-16-44(41-40-25)18-29(47)43-12-10-27-28(17-43)49-33(38-27)39-32(48)24-9-11-42(15-24)19-37/h13-14,16,24H,5-12,15,17-18H2,1-4H3,(H,38,39,48)/t24-/m0/s1
SMILES Code
O=C([C@H]1CCN(C#N)C1)NC2=NC3=C(S2)CN(C(CN4C=C(CCCCC5=C6[N](B(N7C5=C(C)C=C7C)(F)F)=C(C)C=C6C)N=N4)=O)CC3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 688.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Kooij R, Liu S, Sapmaz A, Xin BT, Janssen GMC, van Veelen PA, Ovaa H, Dijke PT, Geurink PP. Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos. J Am Chem Soc. 2020 Sep 30;142(39):16825-16841. doi: 10.1021/jacs.0c07726. Epub 2020 Sep 18. PMID: 32886496; PMCID: PMC7530896.