Plagiochilin A | CAS#91486-94-1 | Inhibitor

MedKoo Cat#: 208519 | Name: Plagiochilin A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Plagiochilin A Inhibits Cytokinetic Abscission and Induces Cell Death

Chemical Structure

Plagiochilin A

CAS#91486-94-1

Theoretical Analysis

MedKoo Cat#: 208519

Name: Plagiochilin A

CAS#: 91486-94-1

Chemical Formula: C15H14O7

Exact Mass: 306.0740

Molecular Weight: 306.27

Elemental Analysis: C, 58.83; H, 4.61; O, 36.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

IUPAC/Chemical Name

4,8-Epoxyfuro(2,3-d)oxepin-2(3H)-one,hexahydro-4,5-dihydroxy-3-((4-hydroxyphenyl)methylene)

InChi Key

PWQBEBGUDFGPIQ-UITAMQMPSA-N

InChi Code

InChI=1S/C15H14O7/c16-8-3-1-7(2-4-8)5-9-11-12(21-13(9)17)10-6-20-14(18)15(11,19)22-10/h1-5,10-12,14,16,18-19H,6H2/b9-5-

SMILES Code

O=C(O1)/C(C2C1C3COC(O)C2(O)O3)=C\C4=CC=C(O)C=C4

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 306.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Stivers NS, Islam A, Reyes-Reyes EM, Casson LK, Aponte JC, Vaisberg AJ, Hammond GB, Bates PJ. Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death. Molecules. 2018 Jun 12;23(6):1418. doi: 10.3390/molecules23061418. PMID: 29895732; PMCID: PMC6099941. Aponte JC, Yang H, Vaisberg AJ, Castillo D, Málaga E, Verástegui M, Casson LK, Stivers N, Bates PJ, Rojas R, Fernandez I, Lewis WH, Sarasara C, Sauvain M, Gilman RH, Hammond GB. Cytotoxic and anti-infective sesquiterpenes present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae). Planta Med. 2010 May;76(7):705-7. doi: 10.1055/s-0029-1240681. Epub 2009 Dec 3. PMID: 19960415.