IUPAC/Chemical Name
6H-(1,3)Dioxolo(5,6)benzofuro(3,2-c)(1)benzopyran-6a(12aH)-ol, 3-methoxy-, (6aR-cis)-
InChi Key
LZMRDTLRSDRUSU-SJORKVTESA-N
InChi Code
InChI=1S/C17H14O6/c1-19-9-2-3-10-12(4-9)20-7-17(18)11-5-14-15(22-8-21-14)6-13(11)23-16(10)17/h2-6,16,18H,7-8H2,1H3/t16-,17+/m1/s1
SMILES Code
O[C@]12COC3=CC(OC)=CC=C3[C@@]1([H])OC4=CC(OCO5)=C5C=C42
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
314.29
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Wasmann CC, Coleman JJ. Screening and Assessment of Pisatin Demethylase Activity (PDA ). Methods Mol Biol. 2022;2391:185-190. doi: 10.1007/978-1-0716-1795-3_15. PMID: 34686986.
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6: Borejsza-Wysocki W, Borejsza-Wysocka E, Hrazdina G. Pisatin metabolism in pea (Pisum sativum L.) cell suspension cultures. Plant Cell Rep. 1997 Feb;16(5):304-309. doi: 10.1007/BF01088286. PMID: 30727668.
7: DiCenzo GL, VanEtten HD. Studies on the late steps of (+) pisatin biosynthesis: evidence for (-) enantiomeric intermediates. Phytochemistry. 2006 Apr;67(7):675-83. doi: 10.1016/j.phytochem.2005.12.027. Epub 2006 Feb 28. PMID: 16504226.
8: PERRIN DR, BOTTOMLEY W. Pisatin: an antifungal substance from Pisum sativum L. Nature. 1961 Jul 1;191:76-7. doi: 10.1038/191076a0. PMID: 13734533.
9: Wu Q, VanEtten HD. Introduction of plant and fungal genes into pea (Pisum sativum L.) hairy roots reduces their ability to produce pisatin and affects their response to a fungal pathogen. Mol Plant Microbe Interact. 2004 Jul;17(7):798-804. doi: 10.1094/MPMI.2004.17.7.798. PMID: 15242174.
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