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MedKoo Cat#: 121031 | Name: CFT-8634

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CFT-8634 is a Transcription Factor PROTAC. CFT-8634 is also an orally bioavailable BRD9 degrader with potential to treat BRD9-dependent tumors.

Chemical Structure

CFT-8634
CFT-8634
CAS#Unknown

Theoretical Analysis

MedKoo Cat#: 121031

Name: CFT-8634

CAS#: Unknown

Chemical Formula: C45H49N5O4

Exact Mass: 723.3785

Molecular Weight: 723.92

Elemental Analysis: C, 74.66; H, 6.82; N, 9.67; O, 8.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
CFT-8634; CFT8634; CFT 8634
IUPAC/Chemical Name
3-(5-(4-((1-(4-((1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
InChi Key
TZZDVPMABRWKIZ-MFTLXVFQSA-N
InChi Code
InChI=1S/C45H49N5O4/c51-37-12-15-39-33(27-37)8-13-38(31-4-2-1-3-5-31)43(39)32-6-9-35(10-7-32)48-20-18-30(19-21-48)28-47-22-24-49(25-23-47)36-11-14-40-34(26-36)29-50(45(40)54)41-16-17-42(52)46-44(41)53/h1-7,9-12,14-15,26-27,30,38,41,43,51H,8,13,16-25,28-29H2,(H,46,52,53)/t38-,41?,43+/m1/s1
SMILES Code
O=C1N(C2C(NC(CC2)=O)=O)CC3=C1C=CC(N(CC4)CCN4CC(CC5)CCN5C6=CC=C(C=C6)[C@H]7[C@@H](C8=CC=CC=C8)CCC9=CC(O)=CC=C97)=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 723.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL