PKI-179 HCl is a second generation, small-molecule mimetic of ATP that targets the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. PKI-179 selectively inhibits mTOR and phosphoinositide-3-kinase (PI3K) alpha. By inhibiting the PI3K/mTOR signaling pathway, this agent may inhibit tumor cell proliferation and survival.
MedKoo Cat#: 471200
Name: PKI-179 HCl
CAS#: 1463510-35-1(HCl)
Chemical Formula: C25H29ClN8O3
Exact Mass: 0.0000
Molecular Weight: 525.01
Elemental Analysis: C, 57.19; H, 5.57; Cl, 6.75; N, 21.34; O, 9.14
The following data is based on the product molecular weight 525.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
