KU-177 is an Aha1 inhibitor which dramatically reduced the accumulation of insoluble tau. Tau forms neurotoxic aggregates that promote cognitive deficits in tauopathies, the most common of which is Alzheimer's disease
MedKoo Cat#: 208365
Name: KU-177
CAS#: unknown
Chemical Formula: C27H23NO8
Exact Mass: 489.1424
Molecular Weight: 489.48
Elemental Analysis: C, 66.25; H, 4.74; N, 2.86; O, 26.15
The following data is based on the product molecular weight 489.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
