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MedKoo Cat#: 556119 | Name: Mebeverine Acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mebeverine acid is a metabolite of the antispasmodic agent mebeverine.

Chemical Structure

Mebeverine Acid
Mebeverine Acid
CAS#475203-77-1

Theoretical Analysis

MedKoo Cat#: 556119

Name: Mebeverine Acid

CAS#: 475203-77-1

Chemical Formula: C16H25NO3

Exact Mass: 279.1834

Molecular Weight: 279.38

Elemental Analysis: C, 68.79; H, 9.02; N, 5.01; O, 17.18

Price and Availability

Size Price Availability Quantity
25mg USD 550.00 2 Weeks
50mg USD 950.00 2 Weeks
100mg USD 1,450.00 2 Weeks
200mg USD 2,450.00 2 Weeks
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Related CAS #
No Data
Synonym
Mebeverine Acid;
IUPAC/Chemical Name
4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]amino]-butanoic acid
InChi Key
UZUWRVLVHOYTNN-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H25NO3/c1-4-17(11-5-6-16(18)19)13(2)12-14-7-9-15(20-3)10-8-14/h7-10,13H,4-6,11-12H2,1-3H3,(H,18,19)
SMILES Code
O=C(O)CCCN(CC)C(C)CC1=CC=C(OC)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 279.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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[Significance of biliary dysfunction in the pathogenesis of gallstone disease]. Eksp Klin Gastroenterol. 2011;(7):70-8. Russian. PMID: 22364003. 13: Walash MI, Kh Sharaf El-Din MM, El-Enany NM, Eid MI, Shalan SM. Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. Chem Cent J. 2012 Feb 14;6:13. doi: 10.1186/1752-153X-6-13. PMID: 22333299; PMCID: PMC3354339. 14: Lipnitskiĭ EM, Isakova OV, Movchun VA, Apdatskaia MD. [Effectiveness of duspatalin therapy in the treatment and prevention of post-cholecystectomy syndrome]. Vestn Ross Akad Med Nauk. 2011;(1):7-11. Russian. PMID: 21395089. 15: Elmasry MS, Blagbrough IS, Rowan MG, Saleh HM, Kheir AA, Rogers PJ. Quantitative HPLC analysis of mebeverine, mesalazine, sulphasalazine and dispersible aspirin stored in a Venalink monitored dosage system with co- prescribed medicines. J Pharm Biomed Anal. 2011 Mar 25;54(4):646-52. doi: 10.1016/j.jpba.2010.10.002. Epub 2010 Oct 14. PMID: 21106317. 16: Walash M, Sharaf El-Din M, El-Enany N, Eid M, Shalan Sh. First derivative synchronous fluorescence spectroscopy for the simultaneous determination of sulpiride and mebeverine hydrochloride in their combined tablets and application to real human plasma. J Fluoresc. 2010 Nov;20(6):1275-85. doi: 10.1007/s10895-010-0679-0. Epub 2010 Jul 7. PMID: 20607372. 17: Abdullah GZ, Abdulkarim MF, Chitneni M, Mutee AF, Ameer OZ, Salman IM, Noor AM. Preparation and in vitro evaluation of mebeverine HCl colon-targeted drug delivery system. Pharm Dev Technol. 2011 Aug;16(4):331-42. doi: 10.3109/10837451003739255. Epub 2010 Apr 30. PMID: 20429815. 18: Maskaoui K, Zhou JL. Colloids as a sink for certain pharmaceuticals in the aquatic environment. Environ Sci Pollut Res Int. 2010 May;17(4):898-907. doi: 10.1007/s11356-009-0279-1. Epub 2009 Dec 19. PMID: 20024675. 19: Lipnitskiĭ EM, Isakova OV, Dzhadzhanidze AD, Ardatskaia MD. 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