Osteoblast differentiation inducer | CAS#364762-78-7 |Inducer

MedKoo Cat#: 208218 | Name: Osteoblast differentiation inducer

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Osteoblast differentiation inducer is an inducer of the differentiation of undifferentiated cells

Chemical Structure

Osteoblast differentiation inducer

CAS#364762-78-7

Theoretical Analysis

MedKoo Cat#: 208218

Name: Osteoblast differentiation inducer

CAS#: 364762-78-7

Chemical Formula: C29H25N3O4S

Exact Mass: 511.1566

Molecular Weight: 511.60

Elemental Analysis: Chemical Formula: C29H25N3O4S Exact Mass: 511.1566 Molecular Weight: 511.5960 Elemental Analysis: C, 68.08; H, 4.93; N, 8.21; O, 12.51; S, 6.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Osteoblastdifferentiationinducer, Osteoblast-differentiation-inducer

IUPAC/Chemical Name

Ethyl 1-methyl-8-(4-(quinolin-2-ylmethoxy)phenoxy)-4,5-dihydro-1H-thieno[3,4-g]indazole-6-carboxylate

InChi Key

IPMNTZSIDFYQQM-UHFFFAOYSA-N

InChi Code

InChI=1S/C29H25N3O4S/c1-3-34-28(33)27-23-15-9-19-16-30-32(2)26(19)25(23)29(37-27)36-22-13-11-21(12-14-22)35-17-20-10-8-18-6-4-5-7-24(18)31-20/h4-8,10-14,16H,3,9,15,17H2,1-2H3

SMILES Code

O=C(C1=C2CCC3=C(N(C)N=C3)C2=C(OC4=CC=C(OCC5=NC6=CC=CC=C6C=C5)C=C4)S1)OCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 511.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

This message contains search results from the National Center for Biotechnology Information (NCBI) at the U.S. National Library of Medicine (NLM). Do not reply directly to this message Sent On: Thu Aug 04 12:50:33 2022 Search: Osteoblast differentiation inducer 10 selected items PubMed Results Items 1-10 of 10 (Display the 10 citations in PubMed) 1: Komori T. Runx2, an inducer of osteoblast and chondrocyte differentiation. Histochem Cell Biol. 2018 Apr;149(4):313-323. doi: 10.1007/s00418-018-1640-6. Epub 2018 Jan 22. PMID: 29356961. 2: Li W, Zhang S, Liu J, Liu Y, Liang Q. Vitamin K2 stimulates MC3T3‑E1 osteoblast differentiation and mineralization through autophagy induction. Mol Med Rep. 2019 May;19(5):3676-3684. doi: 10.3892/mmr.2019.10040. Epub 2019 Mar 15. PMID: 30896842; PMCID: PMC6472126. 3: Ma J, Wang Z, Zhao J, Miao W, Ye T, Chen A. Resveratrol Attenuates Lipopolysaccharides (LPS)-Induced Inhibition of Osteoblast Differentiation in MC3T3-E1 Cells. Med Sci Monit. 2018 Apr 6;24:2045-2052. doi: 10.12659/msm.905703. PMID: 29624568; PMCID: PMC5903312. 4: Komori T. Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2. Int J Mol Sci. 2019 Apr 4;20(7):1694. doi: 10.3390/ijms20071694. PMID: 30987410; PMCID: PMC6480215. 5: Sekiguchi Y, Mano H, Nakatani S, Shimizu J, Kataoka A, Ogura K, Kimira Y, Ebata M, Wada M. Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation. Mol Med Rep. 2017 Aug;16(2):1328-1332. doi: 10.3892/mmr.2017.6752. Epub 2017 Jun 12. PMID: 28627701; PMCID: PMC5562065. 6: Yin N, Zhu L, Ding L, Yuan J, Du L, Pan M, Xue F, Xiao H. MiR-135-5p promotes osteoblast differentiation by targeting HIF1AN in MC3T3-E1 cells. Cell Mol Biol Lett. 2019 Aug 8;24:51. doi: 10.1186/s11658-019-0177-6. PMID: 31410089; PMCID: PMC6686269. 7: Kim YH, Jang WG, Oh SH, Kim JW, Lee MN, Song JH, Yang JW, Zang Y, Koh JT. Fenofibrate induces PPARα and BMP2 expression to stimulate osteoblast differentiation. Biochem Biophys Res Commun. 2019 Dec 3;520(2):459-465. doi: 10.1016/j.bbrc.2019.10.048. Epub 2019 Oct 10. PMID: 31607484. 8: Vidoni C, Ferraresi A, Secomandi E, Vallino L, Gardin C, Zavan B, Mortellaro C, Isidoro C. Autophagy drives osteogenic differentiation of human gingival mesenchymal stem cells. Cell Commun Signal. 2019 Aug 19;17(1):98. doi: 10.1186/s12964-019-0414-7. PMID: 31426798; PMCID: PMC6701103. 9: Zeng HB, Dong LQ, Xu C, Zhao XH, Wu LG. Artesunate promotes osteoblast differentiation through miR-34a/DKK1 axis. Acta Histochem. 2020 Oct;122(7):151601. doi: 10.1016/j.acthis.2020.151601. Epub 2020 Aug 17. PMID: 33066846. 10: Narayanan A, Srinaath N, Rohini M, Selvamurugan N. Regulation of Runx2 by MicroRNAs in osteoblast differentiation. Life Sci. 2019 Sep 1;232:116676. doi: 10.1016/j.lfs.2019.116676. Epub 2019 Jul 21. PMID: 31340165.